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The related main theme: A. Stroke and Cerebral vascular disorders

CORRELATION BETWEEN COAGULATION FACTORS AND STROKE EVENTS IN COVID-19 PATIENTS AT ADAM MALIK MEDAN HOSPITAL AND NETWORK HOSPITAL

Authers:

Conny Theresa Tiharma Napitupulu, MD 1 , Aida  Fithrie, PhD, MD 1 , Cut Aria Arina, PhD, MD 1 , 
1 Department of Neurology, Faculty of Medicine, University of North Sumatra
Corresponding Author:

Conny Theresa Tiharma Napitupulu

keywords: coagulation factor, COVID-19, hemorrhagic stroke, ischemic stroke
Abstract for original article

OBJECTIVES /BACKGROUND:
Stroke in people with COVID-19 may be due to several causes, such as atherosclerosis, hypertension, and atrial fibrillation. Three main mechanisms appear to be responsible for ischemic stroke in COVID-19. These include hypercoagulation states, vasculitis, and cardiomyopathy. This study aims to determine the relationship between coagulation factors and the incidence of stroke in COVID-19 patients.

MATERIAL and METHOD:
This study used a cross sectional design. Sampling was carried out in the inpatient isolation room of the Adam Malik General Hospital Medan and the network hospital as many as 32 subjects. Coagulation factors were examined, namely Prothrombin Time, Activated Partial Thromboplastin Time, Index Normalized Ratio and D-dimer using the Chi Square test.

RESULT:
The characteristics of the 32 research subjects found that the most age was 45 - 65 years as many as 19 subjects (59.4%). The research subjects with the most gender were male as many as 18 subjects (56.3%). The educational level of research subjects was at most undergraduate with 18 subjects (56.3%). Most of the ethnic groups of the research subjects were Javanese as many as 15 subjects (46.9%). For the work of civil servants and housewives as many as 13 subjects (40.6%) respectively. For the most common types of stroke in COVID-19 patients, 24 subjects (75%) were ischemic strokes. In this study, there was no significant relationship between coagulation factors and the incidence of stroke due to the p value> 0.005 using the Chi Square test.

DISCUSSION:
This study found no significant relationship between coagulation factors and the incidence of stroke in COVID-19 patients.


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